• Phone: +91- 9921359485
  • Email: drkatefoundation@gmail.com | info@skrf.org
Helping Us ❤

Our Activities

Introduction

The organization will carry out the following activities towards the objectives:

  • Organize screening camps particularly among scheduled tribe, schedule caste, Nomadic population and OBC population groups.

  • Organize periodic activities in the nature of workshops, lectures by eminent scientists/worker in the field, in social and community settings for increasing awareness of hemoglobinopathies, its cause, preventions, remedies

  • Organize specialized scientific activities in assistive development of existing infrastructure

  • Provide assistance to other organizations working in the field of Hemoglobinopathies.

Tribes Screened

Bhill, Pawara, kokana and Mavachi

  • Tribes of border states of Maharashtra namely Barela of MP (District Barwani, Khargone and Bhill and Pawara community of South Gujarat (Dist. Tapi, Surat and Narmada) have also been sensitized for Sickle Cell disease.

Laboratory Diagnosis of Sickle cell

  • Solubility test reading:
    The Hemoglobin Solubility Test detects Hb S, which is present in individuals with sickle cell anaemia or sickle cell trait. "Solubility" refers to how well a substance dissolves in a liquid. In this case, the substance is the hemoglobin molecule, the major protein in RBCs, and the liquid is blood plasma. Usually, for individuals without sickle cell disease or sickle cell trait, the most common hemoglobin is Hb A, which dissolves quickly in the blood. As a result, the plasma remains clear but will take on a red color. However, the hemoglobin from an individual with sickle cell disease is Hb S. Hb S does not dissolve easily in blood plasma. Instead, the plasma will become cloudy because the Hb S forms tiny crystals. Therefore, a person with the sickle trait will have Hb A and Hb S. They will have some clouding but less than the full-blown sickle cell disease.

Electrophoresis

  • Electropherogram:

    Hemoglobin gel electrophoresis is the most common methodology used for diagnosis. This assay is based upon the association of novel electrophoretic banding patterns with a particular variant of the hemoglobin β proteins that would allow them to be differentiated from one another.

Point of Care kits

  • POC test result:


    POC a rapid test kit for the determination of hemoglobin type in whole blood. This is a competitive lateral flow assay incorporating monoclonal antibodies for detection of hemoglobin A, hemoglobin S, and hemoglobin C. It provides point-of-care determination of hemoglobin phenotypes HbAA (normal), HbSS and HbSC (sickle cell disease), HbCC (hemoglobin C disease), and HbAS and HbAC (carrier or trait). HemoTypeSC™ does not detect other hemoglobin variants (such as Hb D or E) – these variants will give the same result as Hb A. It does not detect – and results are not affected by – fetal hemoglobin, and is therefore suitable for newborn screening..

HPLC testing

  • HPLC instruments:


    The best way to check for sickle cell trait or sickle cell disease is to look at the blood using a method called high-performance liquid chromatography (HPLC). This test identifies which type of hemoglobin is present. To confirm the results of HPLC, a genetic test may be done.

Clinical Examination

  • General examination - Jaundice For other acute and chronic complications and orthopedic complication.

  • Systemic examination pertaining to Sickle Cell Anemia - splenomegaly.

Treatment

  • Hydroxyurea

  • Alternative Anti-sickling Ayurvedic Medicine

  • Supplements & Crises Medicines

Counselling

  • Novel Counselling system using colored cards and table calendar

  • Marriage & Prenatal Diagnosis

Other laboratory investigation

  • Hemoglobin - Using Hemocue Point of care kits

  • Random Sugar – Accucheck Point of care kits

  • Radiological investigations – X rays, Sonography

Manpower development

Workshop

An urgent need-of-hour requirement in the fight against SCD is capacity strengthening of well-trained manpower. This is a herculean task and involves multiple levels from physicians to community healthcare workers.

Zydus Medical College, Dahod, Gujarat.18th & 19th January 2020. 50 Staff, teachers and students attended:


30th June 2022, Nandurbar Medical College, Nandurbar, 250 participants

Webinars

In the first phase of our efforts to address this issue we have organized a series of clinical webinars on symptoms and management of SCA through an online platform. The target audience included physicians mostly from the tribal areas. The details of the webinars are given below.

Webinars conducted by Sudam Kate Research Foundation on various scientific topics related to hemoglobinopathies

Date and Time Topics Speakers
4th October 2020 at 4.00 pm Role of Obstetricians in detection and counseling for Hemoglobinopathies 1. Prof Dr Mrudula Phadke Former Dean BJ Medical College Pune, UNESCO adviser 2. Dr Ruma Manchanda MD (Pathology), Prof. & Director of Pathology, KEM Hospital, Pune. 3. Dr Prakash Gambhir MD (Peadiatric), Director Birthright Clinic Pune. 4. Dr Roshan Colah, PhD, Former Director-in-charge, ICMR National Institute of Immunohematology.
12th October 2020 at 3.30 pm Social and Physiological Stigma of Sickle Cell Disorder: Women Perspective. Prof. Arvind Shaligram, Dr S. L. Kate, Padmashree Dr Anuradha Shrikhande,
18th October 2020 at 4.00 pm “Public Health Aspects of COVID 19 and Tribal Health” Dr Pradip Awate, State Surveillance Officer of Maharashtra
1st November 2020 at 4.00 pm Tribal Health and Addiction issues: A Gadchiroli story "आदिवासींचे आरोग्य आणि व्यासनाधीनता: गडचिरोलीची कहाणी“ Padmashree Dr Abhay Bang, Founder, SEARCH Foundation/td>
6th December at 4.00 pm किशोरवयीन आरोग्याच्या समस्या आणि आदिवासी तरुणांवर अशा समस्यांचा होणारा परिणाम - एक अपवादात्मक वेबिनार An exceptional webinar on Adolescent health problems and the impact of such problems on tribal youth. Padmashree Dr Rani Bang, Director SEARCH Foundation
20th December 2020 at 4.00 pm "Prevalence of HIV and its management in the tribal community of India in the background of Sickle cell Anaemia" "सिकल सेलच्या पार्श्वभूमीवर भारताच्या आदिवासी समाजात एचआयव्हीचा प्रसार आणि त्याचे व्यवस्थापन" Padmashree Dr Raman Gangakhedkar, Head of Epidemiology at the Indian Council of Medical Research, New Delhi
15th January 2022 Clinical Webinar Series – Webinar 1 Frontiers in diagnosis and clinical management of Sickle Cell Anaemia Current Trends and Future Directions./td> Lt Gen (Dr) Madhuri Kanitkar, Hon’ble Vice-Chancellor, MUHS, Nashik. Prof. Graham Sergeant, Chairman of the Sickle Cell Trust (Jamaica) Prof. Dr. Mrudula Phadke, Advisor, National Health Mission, Former Vice Chancelor